The purpose of this systematic review was to compare corticosteroid injections with non-steroidal anti-inflammatory drug (NSAID) injections for musculoskeletal pain. Literature search was conducted to obtain published articles. Articles were considered relevant if they were published in English and if they included data comparing the use of steroids to non-steroidal anti-inflammatory drugs, and included data from more than 50 patients, prednisone for ear fullness. The review included trials that compared the efficacy and safety of corticosteroids to non-steroidal anti-inflammatory drug injections for the treatment of musculoskeletal pain after the use of non-steroidal anti-inflammatory drugs in patients suspected of having either acute or chronic musculoskeletal pain. Data were excluded if: (1) there was a placebo group, (2) the treatment group had received a different dose of steroid, (3) the treatment group did not receive NSAIDs, (4) the treatment group did not have a specific diagnosis, (5) the treatment group received an investigational new drug application or a new FDA approval under this review, or (6) the treatment group was compared to a different type of steroid, ozgear.is review.Findings from the included trial led to eight potential outcomes, including: (1) a significant reduction in pain, (2) a reduction of disability, (3) improvement in function, (4) improvement in quality of life (QoL), and (5) an improvement in joint pain.The authors found that steroids provided significant reductions in pain (P < , best steroid alternative.01, I 2 = 89%), disability (P < , best steroid alternative.001, I 2 = 86%), and QoL (P < , best steroid alternative.001, I 2 = 89%), best steroid alternative.There were significant reductions in joint pain, although they were not related to pain severity. They found a significant reduction in pain and disability, but it was not related to pain severity, ozgear.is review.There were significant reductions in QoL (P < .001, I 2 = 86%). For chronic pain, there were changes in QoL associated with the steroids, but they were not related to pain, anabolic steroid satın al. The authors found that the reduction in pain was significant by comparing the different doses of the steroids, but it was not related to the number of treatments.There was a significant reduction in the quality of life score (P < , anabolic steroids types and uses.001, I 2 = 87%), but it was not related to pain severity, anabolic steroids types and uses. For the duration of treatment, there was a significant reduction in quality of life, but there was no reduction in pain, as the duration of treatment decreased across the different groups.
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